[Futuregen] Cohort paper [revised version]

Fri Nov 26 13:44:25 CET 2021

Congratulations Stefan, and I agree with others (so well put by Afshin!). It’s a beautifully written paper and great comments from others.

I wish you and Johan the very best with the resubmission!

Best wishes,
Janet

Janet Jull, OT Reg (Ont), PhD

Assistant Professor, School of Rehabilitation Therapy,
Queen's University, Kingston, Ontario
janet.jull at queensu.ca
Affiliate Investigator, Ottawa Hospital Research Institute

[cid:6bb850e2-9222-4d38-a6c4-a6627d7a1d75]

Queen's University is situated on traditional Anishinaabe and Haudenosaunee Territory.

________________________________
From: Futuregen <futuregen-bounces at euro.centre.org> on behalf of Stefan Fors <stefan.fors at ki.se>
Sent: November 26, 2021 7:28 AM
To: Afshin Vafaei <vafaei.afshin at gmail.com>; Ricardo Rodrigues <rodrigues at euro.centre.org>
Cc: LIST: FutureGEN <futuregen at euro.centre.org>
Subject: Re: [Futuregen] Cohort paper [revised version]

Dear all,

Thanks a lot for all of your comments and suggestion. I just submitted the revised manuscript – so let’s keep our fingers crossed!

Have a lovely weekend!

Stefan

Från: Afshin Vafaei <vafaei.afshin at gmail.com>
Skickat: den 25 november 2021 18:25
Till: Ricardo Rodrigues <rodrigues at euro.centre.org>
Kopia: Susan Phillips <phillip at queensu.ca>; Stefan Fors <stefan.fors at ki.se>; LIST: FutureGEN <futuregen at euro.centre.org>
Ämne: Re: [Futuregen] Cohort paper [revised version]

Dear Stefan et al.,

I read all your responses, the beautifully composed revised manuscript, and others' comments. All issues have already been covered and I have actually nothing more to add except a few notes that you might (or not) want to add to responses. Just to convince the reviewers that their concerns are well understood and addressed.

1) You clarified in the response that you indeed used average marginal estimates but this is not in the porse except when you talk about the 'margin' command of STATA. A good idea to include this in the manuscript as well.

2) A very good idea that you removed "robustness of the estimates" from the manuscript, a vague term anyway. You may want to clearly say this in the response and also in the manuscript that  collapsing of countries into regions was to increase sample size and hence enhancing statistical power.

3) I hear you and understand the hesitancy for use of an OLS regression for ordinal variables. Generally speaking it is not wrong to do so but interpretation of the coefficients is a little tricky because the variable is in fact not continuous. One way to go around this issue is just to mention the results of the sensitivity analysis in one sentence and add (data not shown, available upon request). And tell the reviewer that you did not want to make the appendix longer unnecessarily.

Fantastic work, I am very positive soon you'll have a publication!

Cheers!

Afshin .

On Wed, Nov 24, 2021 at 4:29 PM Ricardo Rodrigues <rodrigues at euro.centre.org<mailto:rodrigues at euro.centre.org>> wrote:

Dear Stefan, dear Johan,

I read through the changes and replies to the reviewers and I really did not have anything to add, except a couple of suggestions on the "if you really need to" basis below.

Susan mentioned the need for a reference for the use of the square root equivalization: OECD (2011), Divided We Stand – Why Inequality Keeps Rising, Paris.    (www.oecd.org/social/inequality.htm<https://can01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.oecd.org%2Fsocial%2Finequality.htm&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801546478%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=qRxJWmcxWBPNHsBYtiTw9FwwYzWQwVbmZFS7kaEoKws%3D&reserved=0> / www.oecd.org/fr/social/inegalite.htm<https://can01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.oecd.org%2Ffr%2Fsocial%2Finegalite.htm&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801556426%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=JG2CFAuk0gqF%2BdqY%2Fx5M0NToBfADxdxxENPcNN6goCE%3D&reserved=0> ).

I think the reviewers were quite positive on their assessment of the paper in the first place and your replies are to the point and very good.

You argued well enough for using a dichotomous variable. Reviewer 1 was the one who raised this issue and she/he was also the one who thought the results section was already too long: if you want, you can also mention this (text and annexes already too long, as pointed by the said reviewer 😉) to reinforce the use of the dichotomous option only. I would keep the OLS out.

Reviewer 2 mentions the inclusion of complete cases only as a sensitivity analysis - and I think you purposely (and wisely) steered away from opening that can of worms and left this more or less unanswered. 🙂 One argument I could think of, for not using only complete cases (apart from exacerbating attrition), is the fact that we are interested in cohort differences rather than exclusively on longitudinal developments.

It looks very good!

Best wishes,

Ricardo

________________________________

From: Futuregen <futuregen-bounces at euro.centre.org<mailto:futuregen-bounces at euro.centre.org>> on behalf of Susan Phillips <phillip at queensu.ca<mailto:phillip at queensu.ca>>
Sent: Tuesday, November 23, 2021 9:00 PM
To: Stefan Fors <stefan.fors at ki.se<mailto:stefan.fors at ki.se>>
Cc: LIST: FutureGEN <futuregen at euro.centre.org<mailto:futuregen at euro.centre.org>>
Subject: Re: [Futuregen] Cohort paper [revised version]

Hi Stefan,

Your response to reviewers is really clear and covers everything well. I have made a few language edits and a comment or two in the manuscript (attached). I don’t feel like the wisest one to decide about the inclusion of the sensitivity analyses. My sense, from what you have written would be to not include.

Thanks for including me.

Susan

On Nov 22, 2021, at 8:59 AM, Stefan Fors <stefan.fors at ki.se<mailto:stefan.fors at ki.se>> wrote:

Dear friends,

I hope all is well with you! We have now tried to address the comments made by the reviewers for the cohort paper. Please find the revised manuscript, tables and figures, appendix, and responses to the reviewers enclosed. For those of you that are co-authors on the paper – read the revisions and rebuttal letter and let us know what you think (if you have time). The deadline for submission is Friday, so I would need any comments by Thursday in order to make any changes to the manuscript.

One thing Johan and I have been discussing is whether we should include figures from our sensitivity analyses using ordinal indicators of ADL and IADL and OLS-regressions (see attached file) in the response to the reviewers (not for publication). On the one hand, this would serve as a response to their comments on the dichotomization of the outcomes and potential sensitivity analyses. On the other hand, we may invite a whole new host of comments (“why are these not mentioned in the paper?” “why are you using OLS-regressions for ordinal variables?” etc.). So, let us know if you have any opinions on this issue as well.

All the best,

Stefan

Stefan Fors | Forskare

Aging Research Center | Karolinska Institutet

Widerströmska huset, plan 9

Tomtebodavägen 18A  | 171 65 Solna

+46 (0) 703 368 588<tel:+46%20(0)%20703 368%20588>
stefan.fors at ki.se<mailto:stefan.fors at ki.se> | www.ki.se/nvs<https://can01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.ki.se%2Fnvs&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801556426%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=p3BKmX02OOqXrn%2F2Oh84PZNNFGPaIP6MD7EkSNlScY0%3D&reserved=0> | www.ki-su-arc.se<https://can01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.ki-su-arc.se%2F&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801566399%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=fqhdTcli8xuws7bbiCJjHzXMb24Cu8pBF%2FnIJZ3tuJI%3D&reserved=0>

______________________________________

Karolinska Institutet - ett medicinskt universitet

När du skickar e-post till Karolinska Institutet (KI) innebär detta att KI kommer att behandla dina personuppgifter. Här finns information om hur KI behandlar personuppgifter<https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fmedarbetare%2Fintegritetsskyddspolicy&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801566399%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=zgHGip5qMm27HlQTxe3PbhDaCLcLQTK3TAq1KKyoyAw%3D&reserved=0>.

Sending email to Karolinska Institutet (KI) will result in KI processing your personal data. You can read more about KI’s processing of personal data here<https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fstaff%2Fdata-protection-policy&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801576350%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=%2FzTpo8u9bpzQ%2BCHZ9qghKVtZqq0zeAgh%2FfFxfUQAhbQ%3D&reserved=0>.

<Fors et al.R1.docx><Fors et al_Tables and figures_R1.docx><Fors et al_Supplementary materials_R1.docx><adl iadl OLS regressions.pdf><Reply_reviewers_R1.docx>_______________________________________________
Futuregen mailing list
Futuregen at euro.centre.org<mailto:Futuregen at euro.centre.org>
https://lists.euro.centre.org/cgi-bin/mailman/listinfo/futuregen<https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Flists.euro.centre.org%2Fcgi-bin%2Fmailman%2Flistinfo%2Ffuturegen&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801576350%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=m5a3kBLpdjRSs3NdYHQ0hgqfnz4fC7ubNmZgH9lo0io%3D&reserved=0>

Susan Phillips MD, CCFP

Research Director, Centre for Studies in Primary Care

Rosser Research Chair, Family Medicine

Director QuARMS

Queen’s U.

När du skickar e-post till Karolinska Institutet (KI) innebär detta att KI kommer att behandla dina personuppgifter. Här finns information om hur KI behandlar personuppgifter<https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fmedarbetare%2Fintegritetsskyddspolicy&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801576350%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=3cLDZY1mE2zuudxe39tSg8hbrX6BI7%2BwsscT%2BfAsH1M%3D&reserved=0>.

Sending email to Karolinska Institutet (KI) will result in KI processing your personal data. You can read more about KI’s processing of personal data here<https://can01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fki.se%2Fen%2Fstaff%2Fdata-protection-policy&data=04%7C01%7Cjanet.jull%40queensu.ca%7Cef46b5d856884a96587908d9b0d85d91%7Cd61ecb3b38b142d582c4efb2838b925c%7C1%7C0%7C637735266801586302%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000&sdata=dn%2Fw4UoCE50hgRdIOqsYQOu%2BJAPFG18%2FP4HijleCMRM%3D&reserved=0>.
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://lists.euro.centre.org/pipermail/futuregen/attachments/20211126/96a8d9d1/attachment-0001.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: Outlook-p5ab0sc3.png
Type: image/png
Size: 365691 bytes
Desc: Outlook-p5ab0sc3.png
URL: <http://lists.euro.centre.org/pipermail/futuregen/attachments/20211126/96a8d9d1/attachment-0001.png>