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Dear Stefan, dear Johan,<br>
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I read through the changes and replies to the reviewers and I really did not have anything to add, except a couple of suggestions on the "if you really need to" basis below.
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Susan mentioned the need for a reference for the use of the square root equivalization:
<span lang="EN-US">OECD (2011), Divided We Stand – Why Inequality Keeps Rising, Paris.<span style="mso-spacerun:yes">  
</span><o:p> </o:p></span><span style="font-size:11.0pt;line-height:107%;font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:Calibri;mso-fareast-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:Arial;mso-bidi-theme-font:minor-bidi;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-US">(www.oecd.org/social/inequality.htm
 / www.oecd.org/fr/social/inegalite.htm )</span>.</div>
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I think the reviewers were quite positive on their assessment of the paper in the first place and your replies are to the point and very good.</div>
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You argued well enough for using a dichotomous variable. Reviewer 1 was the one who raised this issue and she/he was also the one who thought the results section was already too long: if you want, you can also mention this (text and annexes already too long,
 as pointed by the said reviewer 😉) to reinforce the use of the dichotomous option only. I would keep the OLS out.</div>
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Reviewer 2 mentions the inclusion of complete cases only as a sensitivity analysis - and I think you purposely (and wisely) steered away from opening that can of worms and left this more or less unanswered.
<span id="🙂">🙂</span> One argument I could think of, for not using only complete cases (apart from exacerbating attrition), is the fact that we are interested in cohort differences rather than exclusively on longitudinal developments.<br>
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It looks very good!</div>
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Best wishes,</div>
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Ricardo<br>
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<div id="divRplyFwdMsg" dir="ltr"><font style="font-size:11pt" face="Calibri, sans-serif" color="#000000"><b>From:</b> Futuregen <futuregen-bounces@euro.centre.org> on behalf of Susan Phillips <phillip@queensu.ca><br>
<b>Sent:</b> Tuesday, November 23, 2021 9:00 PM<br>
<b>To:</b> Stefan Fors <stefan.fors@ki.se><br>
<b>Cc:</b> LIST: FutureGEN <futuregen@euro.centre.org><br>
<b>Subject:</b> Re: [Futuregen] Cohort paper [revised version]</font>
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<div class="" style="word-wrap:break-word">Hi Stefan,
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<div class="">Your response to reviewers is really clear and covers everything well. I have made a few language edits and a comment or two in the manuscript (attached). I don’t feel like the wisest one to decide about the inclusion of the sensitivity analyses.
 My sense, from what you have written would be to not include.</div>
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<div class="">Thanks for including me.</div>
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<div class="">Susan</div>
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<blockquote type="cite" class="">
<div class="">On Nov 22, 2021, at 8:59 AM, Stefan Fors <<a href="mailto:stefan.fors@ki.se" class="">stefan.fors@ki.se</a>> wrote:</div>
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<span class="" lang="SV">Dear friends,</span></div>
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I hope all is well with you! We have now tried to address the comments made by the reviewers for the cohort paper. Please find the revised manuscript, tables and figures, appendix, and responses to the reviewers enclosed. For those of you that are co-authors
 on the paper – read the revisions and rebuttal letter and let us know what you think (if you have time). The deadline for submission is Friday, so I would need any comments by Thursday in order to make any changes to the manuscript.</div>
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One thing Johan and I have been discussing is whether we should include figures from our sensitivity analyses using ordinal indicators of ADL and IADL and OLS-regressions (see attached file) in the response to the reviewers (not for publication). On the one
 hand, this would serve as a response to their comments on the dichotomization of the outcomes and potential sensitivity analyses. On the other hand, we may invite a whole new host of comments (“why are these not mentioned in the paper?” “why are you using
 OLS-regressions for ordinal variables?” etc.). So, let us know if you have any opinions on this issue as well.</div>
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All the best,</div>
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Stefan</div>
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<b class=""><span class="" style="font-size:9pt; font-family:Arial,sans-serif" lang="SV">Stefan Fors</span></b><span class="" style="font-size:9pt; font-family:Arial,sans-serif" lang="SV"><span class="x_x_Apple-converted-space"> </span>| Forskare</span></div>
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<span id="x_x_cid:CC471370-9D6E-4911-B10A-3F68DB147720@lan"><Fors et al.R1.docx></span><span id="x_x_cid:7DB38916-8AFD-4D3F-B3BA-B0D0E6314AF5@lan"><Fors et al_Tables and figures_R1.docx></span><span id="x_x_cid:3955314E-7047-4B81-99C9-F7D34DD76A12@lan"><Fors
 et al_Supplementary materials_R1.docx></span><span id="x_x_cid:A6243611-8808-4080-BD34-264BE47A382B@lan"><adl iadl OLS regressions.pdf></span><span id="x_x_cid:EFE23951-35BB-46A6-A5D3-59379796A18D@lan"><Reply_reviewers_R1.docx></span><span class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px; float:none; display:inline!important">_______________________________________________</span><br class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px">
<span class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px; float:none; display:inline!important">Futuregen
 mailing list</span><br class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px">
<a href="mailto:Futuregen@euro.centre.org" class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px">Futuregen@euro.centre.org</a><br class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px">
<a href="https://lists.euro.centre.org/cgi-bin/mailman/listinfo/futuregen" class="" style="font-family:ArialMT; font-size:16px; font-style:normal; font-variant-caps:normal; font-weight:normal; letter-spacing:normal; orphans:auto; text-align:start; text-indent:0px; text-transform:none; white-space:normal; widows:auto; word-spacing:0px">https://lists.euro.centre.org/cgi-bin/mailman/listinfo/futuregen</a></div>
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Susan Phillips MD, CCFP</div>
<div class="">Research Director, Centre for Studies in Primary Care</div>
<div class="">Rosser Research Chair, Family Medicine</div>
<div class="">Director QuARMS</div>
<div class="">Queen’s U.</div>
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